Friday 30 August 2024

 

10% mortality from mRNA vaccine-induced myocarditis

Dr Maarten Fornerod

A Japanese research group has now reported on new analysis that confirms vaccine-induced myocarditis is a serious cause for concern.  Myocarditis is a known serious side effect of mRNA Covid-19 vaccines, mainly affecting young men and boys.

The researchers consulted the passive Japanese adverse event database JADER for this purpose (comparable to the European Eudravigilance or US VAERS databases), for the years 2004 to 2023. They found that, by December 2023:

  • Half of mRNA vaccine-induced myocarditis had completely resolved

  • 25% (Pfizer) and 40% (Moderna) were in remission

  • 7% (Pfizer) and 5% (Moderna) were not cured

  • 6% (Pfizer) and 2% (Moderna) had permanent damage

  • 13% (Pfizer) and 8% (Moderna) had died (see Figure 1).

In approximately half of the reports of myocarditis (919/1846) or pericarditis (321/761), the adverse event was reported from the corona mRNA vaccines.

The authors emphasize that these spontaneous reports do not reflect the real risk of myocarditis or pericarditis after mRNA vaccination, because prospective studies are needed for this. One of the few prospective studies in this area comes from Korea and reports an incidence of myocarditis in boys/young men (13-18 years) of 3.5%.

Outcome of mRNA vaccination induced myocarditis (A-C) and pericarditis (D-F). Figure 4 from (1), colors adjusted for clarity.

During vaccination campaigns, the government, mainstream media and medical organizations usually mention the following points regarding this side effect:

  • the risk of myocarditis due to corona infection is higher than due to vaccination

  • vaccination-induced myocarditis is mild

  • vaccination-induced myocarditis resolves quickly

A comprehensive literature review by Meester and Jacob argues that these three assertions are untenable (p.149-154). Especially in young healthy men, it is very likely that the risk of myocarditis due to vaccination is greater due to vaccination than due to infection. The "mild course" assertion has been refuted by the literature since 2022.

Although the majority of cases are men aged 12-30, a significant minority of cases are women (myocarditis: 22%, pericarditis: 26%) or older than 30 years (myocarditis: 32%, pericarditis: 40%). The complaints start on average 7.36 days after vaccination for myocarditis and 5.89 days for pericarditis.

The WCH advises a moratorium on mRNA vaccinations due to the large number of side effects, including serious, unexplained excess mortality, unexplained birth rate decline and low effectiveness.

1

Takada K, Taguchi K, Samura M, Igarashi Y, Okamoto Y, Enoki Y, Tanikawa K, Matsumoto K. SARS-CoV-2 mRNA vaccine-related myocarditis and pericarditis: An analysis of the Japanese Adverse Drug Event Report database. J Infect Chemother. 2024 Aug 3:S1341-321X(24)00209-5. doi: 10.1016/j.jiac.2024.07.025. Epub ahead of print. PMID: 39103148.

2

Mansanguan, S.; Charunwatthana, P.; Piyaphanee, W.; Dechkhajorn, W.; Poolcharoen, A.; Mansanguan, C. Cardiovascular Manifestation of the BNT162b2 mRNA COVID-19 Vaccine in Adolescents. Trop. Med. Infect. Dis. 2022, 7, 196. https://doi.org/10.3390/tropicalmed7080196

3

Ronald Meester en Marc Jacobs. Eindverslag van het onderzoek naar een mogelijke relatie tussen Covid-19 vaccinaties en oversterfte in Nederland 2021 - 2023. https://www.researchgate.net/publication/383239838_Eindverslag_van_het_onderzoek_naar_een_mogelijke_relatie_tussen_Covid-19_vaccinaties_en_oversterfte_in_Nederland_2021_-_2023

4

Karlstad Ø, Hovi P, Husby A, Härkänen T, Selmer RM, Pihlström N, Hansen JV, Nohynek H, Gunnes N, Sundström A, Wohlfahrt J, Nieminen TA, Grünewald M, Gulseth HL, Hviid A, Ljung R. SARS-CoV-2 Vaccination and Myocarditis in a Nordic Cohort Study of 23 Million Residents. JAMA Cardiol. 2022 Jun 1;7(6):600-612. doi: 10.1001/jamacardio.2022.0583. PMID: 35442390; PMCID: PMC9021987.

5

Kracalik I, Oster ME, Broder KR, Cortese MM, Glover M, Shields K, Creech CB, Romanson B, Novosad S, Soslow J, Walter EB, Marquez P, Dendy JM, Woo J, Valderrama AL, Ramirez-Cardenas A, Assefa A, Campbell MJ, Su JR, Magill SS, Shay DK, Shimabukuro TT, Basavaraju SV; Myocarditis Outcomes After mRNA COVID-19 Vaccination Investigators and the CDC COVID-19 Response Team. Outcomes at least 90 days since onset of myocarditis after mRNA COVID-19 vaccination in adolescents and young adults in the USA: a follow-up surveillance study. Lancet Child Adolesc Health. 2022 Sep 21:S2352-4642(22)00244-9. doi: 10.1016/S2352-4642(22)00244-9. Epub ahead of print. PMID: 36152650.


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